The KRAS Conundrum: Challenges and strategies for targeted therapies in cancer
KRAS is a proto-oncogene that is crucial in regulating cell growth and division. Mutations in the KRAS gene are commonly found in...
September 5, 2024
Ask the Expert: How can patient-derived organoids accelerate KRAS drug development?
RAS proteins have been considered undruggable for several reasons. First, they have a very smooth surface without well-defined binding pockets, making it...
March 14, 2024
Decoding adult stem cells: exploring the hallmarks of stemness
Mammalian organ systems face a constant barrage of internal and external stressors, leading to cellular attrition and functional decline. Maintaining tissue homeostasis...
March 14, 2024
A beginner’s guide to Inflammatory Bowel Diseases (IBD)
Inflammatory Bowel Disease (IBD) is a complex condition that affects millions worldwide. Understanding its nuances is crucial for patients, caregivers, and those...
August 17, 2023
Ask the Experts – organoid & immune cell co-cultures for immunotherapy
In this post of our "Ask the Experts" series, we provide comprehensive answers to frequently asked questions regarding the practical applications of...
March 21, 2023
PDO Screen – Patient-derived Organoids meet Cancer Modeling
Discover how patient-derived organoids can revolutionize oncology research by enabling accurate modeling of tumor biology and predicting patient response to treatment. (more…)
January 16, 2023
The FDA Modernization Act 2.0: A patient-centric paradigm shift in drug development
Explore what the new legislative bill means for the future of organoid technology in drug development The use of animals to test...
November 1, 2022
Challenges in preclinical modeling of cancer immunity
Learn how to select the right model for your immunotherapy development Over the past decade, immunotherapy has revolutionized oncology. From ipilimumab improving...
July 7, 2022
Do you need a license to work with HUB Organoid® Technology?
Explore HUB’s license offerings and how they apply to your organoid research projects HUB’s proprietary technology enables the production of mini-organs in...
May 17, 2022
Forecasting a champion: How HUB Organoids® can speed up the drug development timeline to about five years
Learn why you should invest in patient-derived HUB Organoids® for your drug screening program Drug discovery is like horse betting, except it...
